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Tuberculosis can be considered as an enemy of the mankind. Tuberculosis is not just a serious condition for the person suffering from it but it is also a serious trouble for the person’s family and all the people living in their society. This disease occurs due to a bacteria called Mycobacterium tuberculosis. Tuberculosis is mainly a disease related to lungs but it can also have some effects on the rest of the body. Not only developing countries, but developed countries are also affected by this disease. TB is an infectious disease and can affect persons of all ages, sexes and rich or poor, rural or urban. “Tuberculosis remains a serious health problem worldwide, particularly affecting the poorest in both high-income and developing countries. It was declared a global emergency by the World Health Organization in 1993 (Garcia-Monco, 2014).” “Reconstruction of evolutionary history by Bayesian analysis of extant genome sequences suggests that the Mycobacterium tuberculosis complex emerged as an infection of anatomically modern humans carrying the L3 mitochondrial haplotype around one hundred thousand years ago. (McFadden)"